Screening of Antibiotic-Maggot Serum Combinations and Their Effects on Bacterial Physiology

Author

Arora, Shuchi ; Lim Chu Sing ; Baptista, Carl

Author_Institution

Sch. of Mech. & Aerosp. Eng., Nanyang Technol. Univ., Singapore, Singapore

fYear

2010

fDate

18-20 June 2010

Firstpage

1

Lastpage

4

Abstract

Maggots are known for their anti-microbial properties in chronic wound healing. This paper presents research investigating the effects of maggot metabolites in combination with ciprofloxacin against Staphylococcus aureus. The screening process used was a microchannel-based separation and mixing system. The results demonstrate that for similar levels of efficacy, the partial substitution with the maggot metabolite muted the adoption of antibiotic resistance by the bacteria.

Keywords

antibacterial activity; biochemistry; drugs; microorganisms; Staphylococcus aureus; antibiotic resistance; antibiotic-maggot serum combinations; antimicrobial properties; bacterial physiology; chronic wound healing; ciprofloxacin; maggot metabolites; maggots; microchannel mixing; microchannel-based separation; Anti-bacterial; Antibiotics; Fluids and secretions; Immune system; Medical treatment; Microchannel; Microorganisms; Physiology; Testing; Wounds;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on

Conference_Location

Chengdu

ISSN

2151-7614

Print_ISBN

978-1-4244-4712-1

Electronic_ISBN

2151-7614

Type

conf

DOI

10.1109/ICBBE.2010.5516865

Filename

5516865