Genome-Wide Identification of Orthologs of miR-1302 Genes in Placental Mammals

Author

Yuan, Zhidong ; Sun, Xiao

Author_Institution

State Key Lab. of Bioelectronics, Southeast Univ., Nanjing, China

fYear

2010

fDate

18-20 June 2010

Firstpage

1

Lastpage

4

Abstract

MicroRNAs (miRNAs) are small noncoding RNAs which regulate gene expression. In this research, we used the Multiz alignments data of 44 Vertebrates to retrieve syntenic homolog sequences. And we identified 37 members of miR-1302 family among 71 potential homolog sequences. Then we analyzed the 37 homologs of hsa-mir-1302s by RepeatMasker and found all of these sequences are derived from MER53 elements. Also we show our method is a good way to acquire the orthologs.

Keywords

biological techniques; cellular biophysics; genetics; genomics; molecular biophysics; molecular configurations; MER53 elements; Multiz alignment data; RepeatMasker; gene expression; genome-wide identification; hsa-mir-1302s; miR-1302 family; miR-1302 genes; microRNAs; noncoding RNAs; placental mammals; syntenic homolog sequences; vertebrates; Bioinformatics; Biomedical engineering; Engineering in medicine and biology; Gene expression; Genomics; Horses; Humans; Laboratories; RNA; Sequences;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on

Conference_Location

Chengdu

ISSN

2151-7614

Print_ISBN

978-1-4244-4712-1

Electronic_ISBN

2151-7614

Type

conf

DOI

10.1109/ICBBE.2010.5517434

Filename

5517434