Effects of tissue electrical properties on neural excitation

Author

Grill, Warren M.

Author_Institution

Dept. of Biomed. Eng., Case Western Reserve Univ., Cleveland, OH, USA

Volume

1

fYear

1996

fDate

31 Oct-3 Nov 1996

Firstpage

349

Abstract

The influence of anisotropy and inhomogeneity of tissue electrical conductivity on the relationship between the threshold current and the electrode-to-fiber distance was determined by computer simulation. Anisotropy affected both the slope and offset of the current-distance curve. Inhomogeneity also affected the slope and offset of the current-distance curves, and in some cases caused reversals in recruitment order. This study demonstrates the importance of accurate representation of tissue electrical properties when modeling extracellular electrical stimulation

Keywords

bioelectric phenomena; cellular biophysics; digital simulation; neurophysiology; patient treatment; physiological models; computer simulation; current-distance curve; electrode-to-fiber distance; extracellular electrical stimulation modeling; neural excitation; recruitment order reversals; threshold current; tissue electrical properties effects; tissue electrical properties representation; Anisotropic magnetoresistance; Biological system modeling; Biological tissues; Conductivity; Electrical stimulation; Electrodes; Nerve fibers; Power system modeling; Predictive models; Threshold current;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE

Conference_Location

Amsterdam

Print_ISBN

0-7803-3811-1

Type

conf

DOI

10.1109/IEMBS.1996.656987

Filename

656987