DocumentCode
3218720
Title
Poly(acrylic acid) modified PEG hydrogels
Author
Sipics, J. ; Libera, M.
Author_Institution
Stevens Inst. of Technol., Hoboken, NJ, USA
fYear
2005
fDate
2-3 April 2005
Firstpage
204
Lastpage
205
Abstract
Poly(ethylene glycol) [PEG] hydrogels were synthesized using UV photopolymerization of PEG 575 diacrylate. The swelling of these gels can be controlled by varying the ratio of PEG 575 DA to water in the precursor solution. In the range of 1-10% PEG we observed swelling ratios ranging from 11 down to approximately 5 with the gel brittleness increasing dramatically over this range. We observed that at low pH, 5100 Mw poly(acrylic acid) [PAA] can rapidly infiltrate the PEG gels affecting both their total mass and their swell properties. When immersed in high pH water where PAA deprotonates, the PAA is released over a period of several weeks.
Keywords
biomedical materials; cellular biophysics; gels; pH; polymers; tissue engineering; PEG 575 diacrylate; UV photopolymerization; gel brittleness; hydrogels; pH water; poly(ethylene glycol); swelling; Biological materials; Biomedical engineering; Biomedical materials; Chemical engineering; Chemical technology; Degradation; Electrochemical machining; Extracellular; Mechanical factors; Proteins;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioengineering Conference, 2005. Proceedings of the IEEE 31st Annual Northeast
Print_ISBN
0-7803-9105-5
Electronic_ISBN
0-7803-9106-3
Type
conf
DOI
10.1109/NEBC.2005.1431993
Filename
1431993
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