Parallel flow and mass transfer in polymeric ultrasonic microrresonators

Author

González, Itziar ; Tijero, M. ; Berganzo, J. ; Acosta, V.

Author_Institution

Group of Ultrasounds UMEDIA, Madrid, Spain

fYear

2011

fDate

18-21 Oct. 2011

Firstpage

1541

Lastpage

1544

Abstract

In this work new polymeric microdevices acting as multilayer ultrasonic resonators show their capability and versatility as particle tweezing tools for selective separation or particle sorting. Combination of parallel flows with ultrasonic waves perpendicularly applied allows the mass transfer between them. A strategic position of a pressure node in the channel is required to collect the target cells/particles extracted from their host sample. It is strongly influenced by the 3D vibrational behavior of the plastic structure of the chip. Different chip configurations are being currently developed to optimize the device efficiency of separation, varying two spatial parameters: the distance between the channel and the piezoelectric actuator and the channel length (that is, the relationship between length-width of the chip). Several tests are made on each chip varying the frequency about 12% around the central value of 1MHz to analyze the stability of the pressure node established inside the channel.

Keywords

acoustic resonators; biomedical equipment; biomedical ultrasonics; cancer; cellular biophysics; mass transfer; microactuators; micromechanical resonators; multilayers; piezoelectric actuators; plastics; ultrasonic devices; ultrasonic waves; 3D vibrational behavior; chip configurations; device efficiency; frequency 1 MHz; host sample; length-width relations; mass transfer; multilayer ultrasonic resonators; parallel flow; particle sorting; perpendicular ultrasonic waves; piezoelectric actuator; plastic structure; polymeric microdevices; polymeric ultrasonic microresonators; pressure node; selective separation; spatial parameters; target cell extraction; target particle extraction; tweezing tools; Acoustics; Blood; Force; Nonhomogeneous media; Polymers; Ultrasonic imaging; micromanipulation; microrresonators; particle sorting microfluidics; selective separation;

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics Symposium (IUS), 2011 IEEE International

Conference_Location

Orlando, FL

ISSN

1948-5719

Print_ISBN

978-1-4577-1253-1

Type

conf

DOI

10.1109/ULTSYM.2011.0382

Filename

6293634