Protein microarray chip with embedded microchannels

Author

Tseng, Fan-Gang ; Chen, Y.F. ; Ho, C.E. ; Su, C.J. ; Chen, M.H. ; Lin, S.C. ; Huang, H.M. ; Chieng, C.C.

Author_Institution

Eng. & Syst. Sci. Dept., Nat. Tsing Hua Univ., Hsinchu, Taiwan

Volume

3

fYear

2004

fDate

18-21 Oct. 2004

Firstpage

1773

Abstract

The paper proposes and demonstrates a novel protein microarray chip with an embedded microchannel array for the delivery of protein separately. This chip system is applicable to high throughput disease diagnosis and drug screening. Demonstration in spot formations by the novel design using MEMS technology and characterization of the spot-forming process by numerical simulations are performed to illustrate the feasibility and the advantages of the presented design.

Keywords

biosensors; integrated circuit design; integrated circuit technology; micromechanical devices; proteins; MEMS technology; embedded microchannel array; high throughput disease diagnosis; high throughput drug screening; micro-bio-reaction chip; micro-filling chip; microcontact printing; microfluidic channels; microstamper chip; microstamping; protein microarray chip design; spot formation; Equations; Filling; Microchannel; Numerical simulation; Printing; Protein engineering; Reservoirs; Systems engineering and theory; Testing; Throughput;

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State and Integrated Circuits Technology, 2004. Proceedings. 7th International Conference on

Print_ISBN

0-7803-8511-X

Type

conf

DOI

10.1109/ICSICT.2004.1435176

Filename

1435176