Deformability and viscoelasticity of diabetic erythrocytes measured by microchannel flow system and atomic force microscope

Author

Minamitani, Haruyuki ; Kawamura, Tomomi ; Sekizuka, Eiichi ; Simizu, Tomoya ; Tsukada, Kousuke ; Oshio, Chikara

Author_Institution

Keio Univ., Yokohama, Japan

Volume

1

fYear

1999

fDate

1999

Abstract

Mechanical properties of erythrocytes under diabetic and some other conditions were measured by using transparent micro-channel flow system and atomic force microscope (AFM). Deformability and viscoelasticity of erythrocytes were well correlated both in the healthy control and diabetes mellitus in which the hardness of erythrocytes may affect on the growth of microangiopathy

Keywords

atomic force microscopy; biological techniques; blood; blood flow measurement; cellular transport; diseases; haemorheology; atomic force microscope; deformability; diabetes mellitus; diabetic erythrocytes; growth; hardness; healthy control; mechanical properties; microangiopathy; microchannel flow system; transparent micro-channel flow system; viscoelasticity; Atomic force microscopy; Atomic measurements; Diabetes; Elasticity; Fluid flow measurement; Force measurement; Mechanical factors; Microchannel; Springs; Viscosity;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.802107

Filename

802107