DocumentCode
3311153
Title
Application of genetic algorithm for predicting tertiary structures of peptide chains
Author
Yap, Alex ; Cosic, Irena
Author_Institution
Dept. of Electr. & Comput. Syst. Eng., Monash Univ., Clayton, Vic., Australia
Volume
2
fYear
1999
fDate
36434
Abstract
The protein folding problem is still unsolved due to the large multidimensional conformation space possessed by a protein molecule. The study investigated the application of genetic algorithms (GAs) for the purpose of predicting the tertiary structure of single peptide chains. The search algorithm based on a GA was shown to be superior to a similar scheme using the popular simulated annealing method
Keywords
biology computing; genetic algorithms; macromolecules; molecular biophysics; genetic algorithm; large multidimensional conformation space; protein folding problem; protein molecule; search algorithm; single peptide chains; tertiary structure; Amino acids; Application software; Genetic algorithms; Modeling; Multidimensional systems; Peptides; Protein engineering; Senior members; Simulated annealing; Systems engineering and theory;
fLanguage
English
Publisher
ieee
Conference_Titel
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location
Atlanta, GA
ISSN
1094-687X
Print_ISBN
0-7803-5674-8
Type
conf
DOI
10.1109/IEMBS.1999.804380
Filename
804380
Link To Document