A versatile laboratory platform for studying x-ray 3D breast imaging

Purpose: This paper presents the features of a new laboratory x-ray platform for 3D breast imaging at FDA and initial projection images and tomosynthesis reconstructions. Materials and methods: The laboratory consists of an x- ray generator, x-ray tube and detector, as well as seven step- per motors controlling four linear and three rotary stages. All components are currently being integrated using LabView to allow for an automated operation of the lab. We used 3 different phantoms to obtain initial images. From all the possible geometry arrangements and techniques possible with the system, we selected a breast tomosynthesis acquisition protocol that is similar to those used by systems being investigated or developed by industry. The simultaneous algebraic reconstruction technique (SART) was used to obtain the reconstructions. Results and conclusion: The laboratory provides a flexible platform for performing studies in 3D breast x-ray imaging that can be used to study the effect of different system components on image quality and lead to a better understanding of the system performance.