An automatic gene ontology software tool for bicluster and cluster comparisons

Author

Al-Akwaa, Fadhl M. ; Kadah, Yasser M.

Author_Institution

Univ. of Sci. & Technol., Sana´´a

fYear

2009

fDate

March 30 2009-April 2 2009

Firstpage

163

Lastpage

167

Abstract

We propose an Automatic Gene Ontology (AGO) software as a flexible, open-source Matlab software tool that allows the user to easily compare the results of the bicluster and cluster methods. This software provides several methods to differentiate and compare the results of candidate algorithms. The results reveal that bicluster/cluster algorithms could be considered as integrated modules to recover the interesting patterns in the microarray datasets. The further application of AGO could to solve the dimensionality reduction of the gene regulatory networks.

Keywords

biology computing; cellular biophysics; genetics; mathematics computing; ontologies (artificial intelligence); public domain software; software tools; automatic gene ontology software; bicluster method; cluster method; gene regulatory networks; microarray datasets; open-source Matlab software tool; Bioinformatics; Biological information theory; Clustering algorithms; Gene expression; Genetics; Genomics; Ontologies; Open source software; Software algorithms; Software tools;

fLanguage

English

Publisher

ieee

Conference_Titel

Computational Intelligence in Bioinformatics and Computational Biology, 2009. CIBCB '09. IEEE Symposium on

Conference_Location

Nashville, TN

Print_ISBN

978-1-4244-2756-7

Type

conf

DOI

10.1109/CIBCB.2009.4925723

Filename

4925723