DocumentCode
3398846
Title
Measuring IL-6 and IL-6R Interaction on Single Living Cell Using Nano-Optical Tweezers
Author
Cheng, Wen ; Yan, Zhang ; Anpei, Ye
Author_Institution
Peking Univ., Beijing
fYear
2007
fDate
July 29 2007-Aug. 11 2007
Firstpage
170
Lastpage
171
Abstract
The single molecular level low-affinity between IL-6 and IL-6R was obtained in vivo through the nano-optical tweezers system developed by our group. This affinity is 42.1 plusmn 11.7 pN when the loading rate is 3100 pN-nm/s and the QD accuracy reaches 1 nm.
Keywords
biochemistry; biological techniques; cellular biophysics; molecular biophysics; nanobiotechnology; proteins; radiation pressure; interleukin; nano-optical tweezers; quadrant detector; single living cell; single molecular level low-affinity; Biomedical optical imaging; Biomembranes; Charge carrier processes; Charge coupled devices; Humans; Immune system; In vivo; Nanobioscience; Optical microscopy; Optical noise;
fLanguage
English
Publisher
ieee
Conference_Titel
Nano-Optoelectronics Workshop, 2007. i-NOW '07. International
Conference_Location
Beijing
Print_ISBN
978-1-4244-1591-5
Type
conf
DOI
10.1109/INOW.2007.4302936
Filename
4302936
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