Parameter estimation of a physiological model for heat exchange during cardio-pulmonary bypass

Author

Carta, David Richard

Author_Institution

Dept. of Bioeng., California Univ., San Diego, La Jolla, CA, USA

Volume

2

fYear

1995

fDate

20-23 Sep 1995

Firstpage

1427

Abstract

A model describing relations and interactions between local vessel resistances and tissue temperatures during extra-corporeal circulation (ECC) is described and developed from first principles. Unknown model parameters are estimated by means of an extended Kalman Filter from real patient data. Estimated model parameters produced good model performance in tracking patient data and produced meaningful physiological results. This approach is a necessary first step in modeling further physiological interactions in the body during hypothermic ECC

Keywords

Kalman filters; biothermics; cardiology; heat transfer; lung; parameter estimation; physiological models; cardiopulmonary bypass; estimated model parameters; extended Kalman Filter; extracorporeal circulation; heat exchange physiological model; hypothermia; local vessel resistances; meaningful physiological results; patient data tracking; real patient data; tissue temperatures; unknown model parameters; Biological system modeling; Blood; Cardiology; Circuits; Electric resistance; Heat transfer; Immune system; Parameter estimation; Surgery; Temperature;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference

Conference_Location

Montreal, Que.

Print_ISBN

0-7803-2475-7

Type

conf

DOI

10.1109/IEMBS.1995.579760

Filename

579760