Intensity-based feedback of the thermally induced denaturation of collagen

Author

Maitland, Duncan J. ; Walsh, Joseph T., Jr.

Author_Institution

Dept. of Biomed. Eng., Northwestern Univ., Evanston, IL, USA

Volume

2

fYear

1995

fDate

20-23 Sep 1995

Firstpage

1735

Abstract

Since the birefringent property of collagenous tissue results in a phase shift between scattered orthogonal linear polarizations, this phase shift was used to develop an intensity based measurement technique of birefringence. If the two orthogonal polarizations are coupled into a common linear polarization then interference, and thus intensity, may be used to dynamically measure denaturation-associated birefringence losses. Excellent agreement between the theory and experiments were obtained

Keywords

biological techniques; biothermics; birefringence; feedback; molecular biophysics; molecular configurations; proteins; birefringent property; collagen; collagenous tissue; common linear polarization; denaturation-associated birefringence losses; intensity based measurement technique; intensity-based feedback; interference; orthogonal polarizations; quantitative techniques; thermally induced denaturation; Feedback; Heating; Lenses; Microscopy; Monitoring; Polarization; Rats; System testing; Temperature; Tendons;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference

Conference_Location

Montreal, Que.

Print_ISBN

0-7803-2475-7

Type

conf

DOI

10.1109/IEMBS.1995.579916

Filename

579916