A 0.18μm CMOS Integrated Sensor for the Rapid Identification of Bacteria

This paper presents an integrated sensor for identifying bacteria that addresses drawbacks of traditional detection techniques by combining the specificity of phages with the sensitivity of integrated electronic circuits. This is the first silicon-based implementation known to date; it uses standard CMOS technology, does not require noble-metal electrodes and co-integrates active circuitry on the same substrate as the measurement site containing the bacteria. The chip was fabricated in 0.18 mum CMOS technology using thick-oxide transistors and consumes 122 muW with a 3.3 V supply for two recording channels.