A graphene-based affinity glucose nanosensor

Affinity glucose sensors based on equilibrium binding can offer improved stability and accuracy for continuous glucose monitoring in diabetes care. This paper presents a graphene-based affinity nanosensor for glucose measurements. The nanosensor exploits the affinity binding of a novel, surface-immobilized synthetic polymer with glucose. The binding induces changes in the bulk electrical properties of graphene, which are measured for sensitive glucose detection in a highly miniaturized device without the use of physical barriers commonly employed by existing affinity glucose sensors.