Effect of intraluminal thrombus on local abdominal aortic aneurysm wall strength

Author

Wang, D.H.J. ; Schiro, B.J. ; Makaroun, M.S. ; Webster, M.W. ; Vorp, D.A.

Author_Institution

Dept. of Surg. & Bioeng., Pittsburgh Univ., PA, USA

Volume

1

fYear

1999

fDate

1999

Abstract

We have shown that the intraluminal thrombus (ILT) commonly found within abdominal aortic aneurysm (AAA) significantly attenuates diffusion of oxygen to the aortic wall as its thickness increases. We hypothesize that, as a result, the strength of the AAA wall is inversely related to ILT thickness. We tested the strength of 6 pairs of freshly excised AAA wall specimens from 6 different patients. Uniaxial tensile testing revealed that AAA wall adjacent to thin ILT or no ILT is significantly stronger than that adjacent to thick ILT (p=0.03)

Keywords

biodiffusion; biomechanics; blood vessels; diseases; O₂; diffusion; freshly excised abdominal aortic aneurysm wall specimens; intraluminal thrombus; intraluminal thrombus thickness; local abdominal aortic aneurysm wall strength; patients; uniaxial tensile testing; Abdomen; Aneurysm; Bars; Biomedical engineering; Biomedical measurements; Diseases; History; Surgery; Tensile stress; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.802299

Filename

802299