Modeling and identification of cardiovascular hemodynamics in a closed-loop model with ventricular interaction

Author

Olansen, J.B. ; Clark, J.W. ; Khoury, D. ; Ghorbel, F. ; Bidani, A.

Author_Institution

Dept. of Mech. Eng., Rice Univ., Houston, TX, USA

Volume

1

fYear

1999

fDate

1999

Abstract

A closed-loop model of the cardiopulmonary circulation has been developed for the study of right-left heart interaction under physiologically normal and altered conditions. Model parameters are identified via comparison with canine hemodynamic data using a Levenberg-Marquardt algorithm. The core model provides insight into the affects of ventricular interaction and the pericardium on hemodynamics. Alterations of model parameters can be used to predict the impact of disease and/or clinical interventions on steady-state hemodynamic performance

Keywords

cardiovascular system; haemodynamics; parameter estimation; physiological models; Levenberg-Marquardt algorithm; canine hemodynamic data; cardiopulmonary circulation; cardiovascular hemodynamics identification; cardiovascular hemodynamics modeling; closed-loop model; disease impact prediction; model parameters identification; physiologically altered conditions; physiologically normal conditions; right-left heart interaction; steady-state hemodynamic performance; Biomedical engineering; Biomedical imaging; Cardiology; Circuits; Educational institutions; Heart; Hemodynamics; Mechanical engineering; Parameter estimation; Transducers;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.802311

Filename

802311