Effects of iron oxide magnetic nanoparticles on osteoblast proliferation

Author

Tran, N. ; Pareta, Rajesh ; Webster, Thomas

Author_Institution

Dept. of Phys., Brown Univ., Providence, RI

fYear

2009

fDate

3-5 April 2009

Firstpage

1

Lastpage

2

Abstract

Iron oxide nanoparticles are promising candidates for drug delivery systems to treat osteoporosis due to their biocompatibility and magnetic properties. Magnetite and maghemite nanoparticles were synthesized here using a co-precipitation method. The particles were characterized by transmission electron microscopy (TEM). Effects of CaP coating iron oxide magnetic nanoparticles on the proliferation of osteoblasts (OB) were determined after 1, 3 and 5 days of culture. The correlation of iron oxide nanoparticle concentration on OB density was also investigated.

Keywords

biomagnetism; biomedical materials; bone; calcium compounds; coatings; drug delivery systems; iron compounds; nanobiotechnology; CaP; CaP coating; Fe₂O₃; Fe₃O₄; biocompatibility; coprecipitation method; drug delivery systems; iron oxide magnetic nanoparticles; maghemite nanoparticles; magnetite nanoparticles; osteoblast proliferation; osteoporosis; transmission electron microscopy; Amorphous magnetic materials; Bones; Calcium; Drug delivery; Iron; Magnetic properties; Magnetosphere; Nanoparticles; Osteoporosis; Saturation magnetization;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 2009 IEEE 35th Annual Northeast

Conference_Location

Boston, MA

Print_ISBN

978-1-4244-4362-8

Electronic_ISBN

978-1-4244-4364-2

Type

conf

DOI

10.1109/NEBC.2009.4967626

Filename

4967626