Perturbation solution for stress-induced fluid flow within anisotropic nonhomogeneous osteons

Stress-induced fluid flow within individual osteons is modeled using a perturbation technique. In contrast to earlier models, the first order solution shows that flow within the mineralized matrix can occur in the longitudinal direction, suggesting a possible non-canalicular osteocytic nutrient supply route. The model also suggests that stress-induced streaming potentials within osteons arise in part due to anisotropic permeability