Long-range surface plasmon-polariton waveguide biosensors for disease detection

We review recent progress on the application of long-range surface plasmon-polariton waveguide biosensors for disease detection. The biosensors are constructed from metal stripe waveguides cladded in Cytop with etched microfluidic channels to expose the stripe surface to the sensing fluid. The waveguides support long-range surface plasmons in integrated optics geometries when excited in an end-fire manner. Application to the detection of leukemia, dengue fever, and urinary tract infection is discussed.