• DocumentCode
    419049
  • Title

    Parameter optimization of an evolutionary algorithm for RNA structure discovery

  • Author

    Fogel, Gary B. ; Weekes, Dana G. ; Sampath, Rangarajan ; Ecker, David J.

  • Author_Institution
    Natural Selection, Inc., La Jolla, CA, USA
  • Volume
    1
  • fYear
    2004
  • fDate
    19-23 June 2004
  • Firstpage
    607
  • Abstract
    This paper focuses on the optimization of population and selection parameters of an evolutionary algorithm for similar RNA structure discovery. The effects of population settings such as the number of parents and number of offspring per parent, and method of selection (tournament vs. elitist) on the rate of convergence were investigated relative to a problem with a known RNA structure solution. The results indicate that proper setting of the number of parents and offspring can be used to increase the efficiency of the evolutionary process.
  • Keywords
    biology computing; convergence; evolutionary computation; genetics; macromolecules; optimisation; RNA structure discovery; evolutionary algorithm; parameter optimization; Bioinformatics; Databases; Drugs; Evolutionary computation; Genomics; Organisms; Phylogeny; RNA; Space exploration; Stability;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Evolutionary Computation, 2004. CEC2004. Congress on
  • Print_ISBN
    0-7803-8515-2
  • Type

    conf

  • DOI
    10.1109/CEC.2004.1330913
  • Filename
    1330913