DocumentCode
419049
Title
Parameter optimization of an evolutionary algorithm for RNA structure discovery
Author
Fogel, Gary B. ; Weekes, Dana G. ; Sampath, Rangarajan ; Ecker, David J.
Author_Institution
Natural Selection, Inc., La Jolla, CA, USA
Volume
1
fYear
2004
fDate
19-23 June 2004
Firstpage
607
Abstract
This paper focuses on the optimization of population and selection parameters of an evolutionary algorithm for similar RNA structure discovery. The effects of population settings such as the number of parents and number of offspring per parent, and method of selection (tournament vs. elitist) on the rate of convergence were investigated relative to a problem with a known RNA structure solution. The results indicate that proper setting of the number of parents and offspring can be used to increase the efficiency of the evolutionary process.
Keywords
biology computing; convergence; evolutionary computation; genetics; macromolecules; optimisation; RNA structure discovery; evolutionary algorithm; parameter optimization; Bioinformatics; Databases; Drugs; Evolutionary computation; Genomics; Organisms; Phylogeny; RNA; Space exploration; Stability;
fLanguage
English
Publisher
ieee
Conference_Titel
Evolutionary Computation, 2004. CEC2004. Congress on
Print_ISBN
0-7803-8515-2
Type
conf
DOI
10.1109/CEC.2004.1330913
Filename
1330913
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