Design study of an MRI compatible ultra-high resolution SPECT for in vivo mice brain imaging

Author

Meng, Ling-Jian ; Tan, Jia-Wei ; Fu, Geng

Author_Institution

Univ. of Illinois at Urbana-Champaign, Urbana

Volume

4

fYear

2007

fDate

Oct. 26 2007-Nov. 3 2007

Firstpage

2956

Lastpage

2960

Abstract

This paper presents the design study of an MRI compatible, ultra-high resolution SPECT system. This system consists of multiple ultra-high resolution energy-resolved photon counting (ERPC) CdTe detectors that are currently development. This detector is based on a novel readout ASIC that is roughly 1.1times2.2 cm² in size and has a 32times64 array of 350times350 um² pixels. A prototype detector was tested inside a 4.7 Tesla MRI scanner for simple pinhole imaging. The results obtained have demonstrated the feasibility of simultaneous acquisition of SPECT and MRI data. Extensive Monte Carlo simulation was performed to evaluate a number of system configurations.

Keywords

Monte Carlo methods; application specific integrated circuits; biomedical MRI; brain; image resolution; neurophysiology; single photon emission computed tomography; solid scintillation detectors; ASIC readout; CdTe detector; MRI compatible SPECT; Monte Carlo simulation; energy-resolved photon counting; in vivo mice brain imaging; magnetic flux density 4.7 T; pinhole imaging; Application specific integrated circuits; Brain; Detectors; Energy resolution; Image resolution; In vivo; Magnetic resonance imaging; Mice; Sensor arrays; Single photon emission computed tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2007. NSS '07. IEEE

Conference_Location

Honolulu, HI

ISSN

1095-7863

Print_ISBN

978-1-4244-0922-8

Electronic_ISBN

1095-7863

Type

conf

DOI

10.1109/NSSMIC.2007.4436754

Filename

4436754