• DocumentCode
    4815
  • Title

    Automatic Detection of Optic Disc Based on PCA and Mathematical Morphology

  • Author

    Morales, S. ; Naranjo, V. ; Angulo, J. ; Alcaniz, Mariano

  • Author_Institution
    Inst. Interuniversitario de Investig. en Bioingenieria y Tecnol. Orientada al Ser Humano, Univ. Politec. de Valencia, Valencia, Spain
  • Volume
    32
  • Issue
    4
  • fYear
    2013
  • fDate
    Apr-13
  • Firstpage
    786
  • Lastpage
    796
  • Abstract
    The algorithm proposed in this paper allows to automatically segment the optic disc from a fundus image. The goal is to facilitate the early detection of certain pathologies and to fully automate the process so as to avoid specialist intervention. The method proposed for the extraction of the optic disc contour is mainly based on mathematical morphology along with principal component analysis (PCA). It makes use of different operations such as generalized distance function (GDF), a variant of the watershed transformation, the stochastic watershed, and geodesic transformations. The input of the segmentation method is obtained through PCA. The purpose of using PCA is to achieve the grey-scale image that better represents the original RGB image. The implemented algorithm has been validated on five public databases obtaining promising results. The average values obtained (a Jaccard´s and Dice´s coefficients of 0.8200 and 0.8932, respectively, an accuracy of 0.9947, and a true positive and false positive fractions of 0.9275 and 0.0036) demonstrate that this method is a robust tool for the automatic segmentation of the optic disc. Moreover, it is fairly reliable since it works properly on databases with a large degree of variability and improves the results of other state-of-the-art methods.
  • Keywords
    differential geometry; eye; image segmentation; mathematical morphology; medical image processing; principal component analysis; stochastic processes; Dice coefficients; Jaccard coefficients; PCA; RGB image; automatic detection; automatic segmentation; fundus image; generalized distance function; geodesic transformations; grey-scale image; mathematical morphology; optic disc contour extraction; principal component analysis; public databases; segmentation method; stochastic watershed; watershed transformation; Biomedical optical imaging; Databases; Image segmentation; Morphology; Optical imaging; Principal component analysis; Probability density function; Generalized distance function; geodesic transformation; optic disc; principal component analysis; watershed transformation; Adult; Aged; Algorithms; Female; Fundus Oculi; Glaucoma; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Ocular Hypertension; Optic Disk; Principal Component Analysis; Reproducibility of Results;
  • fLanguage
    English
  • Journal_Title
    Medical Imaging, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0278-0062
  • Type

    jour

  • DOI
    10.1109/TMI.2013.2238244
  • Filename
    6408254