Bone/HA interface behaviour during physiopathological processes in the periodontal bone

This study demonstrates that the specific interface obtained after HA ceramics implantation is controlled by the physico-chemical process of dissolution/precipitation. The process is related to biological apatite crystals closely associated with the residual HA crystals. This interface is not static, it is submitted to biological evolution. Especially in mandibular area submitted to numerous stresses and disease, the equilibrium between dissolution/precipitation/bone substitution may be easily changed and may compromise the success of HA bone filling or bone augmentation.