Multiscale entropy indicates vascular abnormalities in the aged

Author

Lee, Chun-Ho ; Chen, Guan-hong ; Wu, Hsien-Tsai ; Lo, Men-Tzung ; Sun, Cheuk-Kwan ; Tang, Chieh-Ju

Author_Institution

Dept. of Electr. Eng., Nat. Dong Hwa Univ., Hualien, Taiwan

Volume

1

fYear

2011

fDate

10-13 July 2011

Firstpage

80

Lastpage

84

Abstract

This study investigates the feasibility and sensitivity of a novel multiscale entropy index (MEI) in detecting subtle endothelial dysfunction in young and middle-aged subjects. Between December 2009 and May 2010, totally 70 subjects were recruited from a hospital, and categorized into young group (Group 1), middle-aged or elderly group (Group 2). Arterial pulse wave signals were acquired from the wrist with air pressure sensing system (APSS), followed by MEI and dilatation index (DI) analyses. In conclusion, a reduction in multiscale entropy reflected age related vascular changes and may serve as a more sensitive indicator of subtle endothelial dysfunction compared with DI in the setting of aged.

Keywords

biomedical measurement; blood vessels; cardiovascular system; diseases; geriatrics; pressure sensors; air pressure sensing system; arterial pulse wave signals; dilatation index; elderly group; endothelial dysfunction; middle-aged subjects; multiscale entropy index; vascular abnormalities; young subjects; Aging; Complexity theory; Diabetes; Entropy; Indexes; Senior citizens; Wrist; Air pressure sensing system; Dilatation index; Endothelial function; Multiscale entropy;

fLanguage

English

Publisher

ieee

Conference_Titel

Machine Learning and Cybernetics (ICMLC), 2011 International Conference on

Conference_Location

Guilin

ISSN

2160-133X

Print_ISBN

978-1-4577-0305-8

Type

conf

DOI

10.1109/ICMLC.2011.6016687

Filename

6016687