• DocumentCode
    573710
  • Title

    Analysis of a HBV infection model with non-cytolytic cure process

  • Author

    Zhuo, Xinjian

  • Author_Institution
    Sch. of Sci., Beijing Univ. of Posts & Telecommun., Beijing, China
  • fYear
    2012
  • fDate
    18-20 Aug. 2012
  • Firstpage
    148
  • Lastpage
    151
  • Abstract
    Mathematical models have been used to understand the factors that govern infectious disease progression in viral infections. Many models ignore the loss term of free virus particle when it enters the target cell. In this paper, we discuss a virus infection model with the loss term of free virus and the non-cytolytic loss of infected cells. Stable analysis of our model was given. If the basic reproduction number R0 <; 1, the infection-free equilibrium is globally asymptotically stable and the virus is cleared; if the basic reproduction number R0 >; 1, then the virus would persist in the host.
  • Keywords
    cellular biophysics; diseases; microorganisms; physiological models; HBV infection model analysis; free virus particle; globally asymptotically stable; infected cells; infectious disease progression; mathematical models; noncytolytic cure processing; noncytolytic loss; stable analysis; virus infection model; Analytical models; Asymptotic stability; Equations; Jacobian matrices; Mathematical model; Stability analysis; Steady-state; Mathematical model; stable analysis; virus dynamics;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Systems Biology (ISB), 2012 IEEE 6th International Conference on
  • Conference_Location
    Xi´an
  • Print_ISBN
    978-1-4673-4396-1
  • Electronic_ISBN
    978-1-4673-4397-8
  • Type

    conf

  • DOI
    10.1109/ISB.2012.6314127
  • Filename
    6314127