Research on optical biological sensor used as quantitative analysis of glucose

In this paper, we designed and fabricated the biological sensor structure on silicon-based chip and then fixed glucose oxidase molecular on the silicon wafer in chemical bond forms through surface oxidation activation, silane coupling agent deposition, link molecules fixing and glucose oxidase linking. Micro-ring resonator with whispering gallery mode is developed to improve the Q factor and thus enhance the sensitivity of the bio-sensor. In this way, quantitative analysis of the glucose in the test liquid can be achieved through the biological sensor by measuring the shift of the resonant wavelength in transmission spectrum.