DocumentCode
662918
Title
Estimation of internal variables from Hodgkin-Huxley neuron voltage
Author
Sinha, Aloka ; Schiff, S.J. ; Huebel, Nico
Author_Institution
Center of Neural Eng. & Mech. Eng. Dept., Pennsylvania State Univ., University Park, PA, USA
fYear
2013
fDate
6-8 Nov. 2013
Firstpage
194
Lastpage
197
Abstract
This paper presents a novel approach to estimate internal variables such as gating variables, potassium, sodium and chloride concentrations from the knowledge of voltage of a neuron. This approach is based on the Hodgkin-Huxley neuron dynamics and basic ideas behind a Luenberger observer, and utilizes the full nonlinear dynamics. Results from numerical simulations are presented.
Keywords
bioelectric phenomena; biomembrane transport; chlorine; nonlinear dynamical systems; numerical analysis; potassium; sodium; Cl; Hodgkin-Huxley neuron nonlinear dynamics; Hodgkin-Huxley neuron voltage; K; Na; chloride concentrations; gating variable estimation; internal variable estimation; numerical simulations; potassium concentrations; sodium concentrations; Equations; Extracellular; Mathematical model; Neurons; Observers; Voltage measurement;
fLanguage
English
Publisher
ieee
Conference_Titel
Neural Engineering (NER), 2013 6th International IEEE/EMBS Conference on
Conference_Location
San Diego, CA
ISSN
1948-3546
Type
conf
DOI
10.1109/NER.2013.6695905
Filename
6695905
Link To Document