DocumentCode
703746
Title
Understanding SNP — Gene associations in pancreatic cancer: A systems biology approach
Author
Joseph, Nimish ; Gopakumar, G. ; Pradhan, Meeta ; Abdul Nazeer, K.A. ; Palakal, Mathew J.
Author_Institution
Dept. of Comput. Sci. & Eng., Nat. Inst. of Technol., Kozhikode, India
fYear
2015
fDate
19-21 Feb. 2015
Firstpage
1
Lastpage
5
Abstract
The findings of Human Genome Project revealed Single Nucleotide Polymorphisms (SNPs) as the most common form of genetic variations in humans. It also demonstrated the active role of SNPs in the genesis of many system disorders. Thus it is related to one or more diseases. SNP-Gene interactions across multiple diseases is a novel area of research which can result in understanding its commonality or uniqueness across population or disease clusters. This study with Pancreatic Cancer data gives a better and faster approach to make use of these associations and thereby to help in determining the disease causing SNPs and Genes which are common or unique across the disease cluster.
Keywords
bioinformatics; biomedical engineering; cancer; genetics; SNP-gene interaction; disease cluster; gene association; pancreatic cancer data; single nucleotide polymorphism; Bioinformatics; Cancer; Diseases; Genomics; Systems biology; SNP; SNP-Gene Interaction; Systems Biology; drug discovery; genes;
fLanguage
English
Publisher
ieee
Conference_Titel
Signal Processing, Informatics, Communication and Energy Systems (SPICES), 2015 IEEE International Conference on
Conference_Location
Kozhikode
Type
conf
DOI
10.1109/SPICES.2015.7091515
Filename
7091515
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