Magnetic Particle Spectroscopy to monitor the behavior of magnetic nanoparticles in different physiological media

Author

Radon, P. ; Lowa, N. ; Wiekhorst, F. ; Trahms, L.

Author_Institution

Phys.-Tech. Bundesanstalt, Berlin, Germany

fYear

2015

fDate

26-28 March 2015

Firstpage

1

Lastpage

1

Abstract

Magnetic Particle Imaging (MPI) is a promising tomographic modality using magnetic nanoparticles (MNP) as probes for diagnostic purposes in biomedicine. The MPI signal quality crucially depends on the magnetic properties of the MNP as well as on the influence of the surrounding biological environment. Therefore, different physiological parameters like pH-value, salt concentration, mobility may have distinct impact on the MPI signal performance. We used Magnetic Particle Spectroscopy, the zero-dimensional MPI, to monitor the potential MPI performance of Resovist and Feraheme MNP in different physiological media as a function of time.

Keywords

biomagnetism; biomedical imaging; magnetic particles; nanomagnetics; nanomedicine; nanoparticles; pH; Feraheme; MPI signal performance; MPI signal quality; Resovist; biological environment; biomedicine; diagnostic purposes; magnetic nanoparticles; magnetic particle imaging; magnetic particle spectroscopy; mobility; pH-value; physiological media; physiological parameters; salt concentration; tomographic modality; zero-dimensional MPI; Biomedical monitoring; Harmonic analysis; Magnetic particles; Media; Monitoring; Temperature measurement; Temperature sensors;

fLanguage

English

Publisher

ieee

Conference_Titel

Magnetic Particle Imaging (IWMPI), 2015 5th International Workshop on

Conference_Location

Istanbul

Print_ISBN

978-1-4799-7269-2

Type

conf

DOI

10.1109/IWMPI.2015.7107007

Filename

7107007