Microelectrod fabrication for diagnosis and treatment of brain disorders

Author

Acar, Merve ; Shamsi, Hamed ; Oyar, Oguzhan ; Ozbek, I. Yucel ; Hacimuftuoglu, Ahmet ; Cavusoglu, Bulent ; Oral, E. Argun ; Karacali, Tevhit ; Sonmez, Erdal ; Ertugrul, Mehmet ; Efeoglu, Hasan

Author_Institution

Elektrik ve Elektron. Muhendisligi, ATATURK Univ., Erzurum, Turkey

fYear

2015

fDate

16-19 May 2015

Firstpage

2058

Lastpage

2061

Abstract

In this study, it is aimed to produce microelectrodes which can be used in the detection of neurotransmitters that are related with brain disorders such as Parkinson, Epilepsy, and Schizophrenia and that exist in the central nervous system (CNS). A 4-channel, ceramic-based fabrication is performed towards this goal by using photolithographic methods. The time-current graphic response against the addition of H₂O₂ the produced microelectrode is analyzed in the calibration test. It is observed that the response is in stepwise form. In addition, limit of detection (LOD) of the produced microelectrodes and linearity values are shown to be within the desired ranges.

Keywords

brain; calibration; ceramics; microelectrodes; neurophysiology; patient diagnosis; patient treatment; photolithography; 4-channel ceramic-based fabrication; Parkinson; brain disorder diagnosis; brain disorder treatment; calibration test; central nervous system; epilepsy; microelectrode fabrication; neurotransmitters detection; photolithographic methods; schizophrenia; time-current graphic response; Biomedical measurement; Fabrication; Films; In vivo; Metals; Microelectrodes; Neurotransmitters; biosensor; fabrication; microelectrode; voltametry;

fLanguage

English

Publisher

ieee

Conference_Titel

Signal Processing and Communications Applications Conference (SIU), 2015 23th

Conference_Location

Malatya

Type

conf

DOI

10.1109/SIU.2015.7130273

Filename

7130273