DocumentCode
733239
Title
Ellipsometry-based opto-fluidic platform for characterizing 10,000 biomolecular reactions on solid supports in real time and for identifying inhibitors against protein-receptor interactions
Author
Zhu, X.D.
Author_Institution
Dept. of Phys., Univ. of California at Davis, Davis, CA, USA
fYear
2015
fDate
10-15 May 2015
Firstpage
1
Lastpage
2
Abstract
We developed an optical detection platform based on nulling ellipsometry for simultaneously characterizing 10,000 biomolecular reactions on solid supports and for highly efficient identification of inhibitory molecules against specific protein-protein interactions from large compound libraries.
Keywords
biochemistry; ellipsometry; molecular biophysics; proteins; biomolecular reactions; ellipsometry-based optofluidic platform; inhibitory molecules; nulling ellipsometry; optical detection platform; protein-protein interactions; protein-receptor interactions; Biomedical optical imaging; Compounds; Glass; Inhibitors; Probes; Proteins; Real-time systems;
fLanguage
English
Publisher
ieee
Conference_Titel
Lasers and Electro-Optics (CLEO), 2015 Conference on
Conference_Location
San Jose, CA
Type
conf
Filename
7183676
Link To Document