• DocumentCode
    790024
  • Title

    Computing life´s family tree [phylogeny]

  • Author

    Gorder, P.F.

  • Volume
    7
  • Issue
    3
  • fYear
    2005
  • Firstpage
    3
  • Lastpage
    6
  • Abstract
    Call it yet another biological gold rush. When Charles Darwin published The Origin of Species in 1859, scientists began working in earnest to document the world´s plant and animal species and build a phylogeny - a map of how all those species relate to each other. More scientists came to the discipline in the 1980s, when automated DNA sequencing offered a way to classify species and applications for phylogenetics. Thanks to such efforts, at least a small sample of genetic code is on file in databases worldwide for some 100,000 of Earth´s organisms. The largest such database, GenBank, contains more than 42.7 million genetic sequences, and counting. But scientists have yet to realize Darwin´s phylogeny; they´ve sampled genes piecemeal - a rice gene here, a mouse protein there - and have connected relatively few species. Today, the prospectors in the gold rush are those with enough expertise in computing to connect all that genetic data in a meaningful way. The goal is the same as it was 150 years ago: build the ultimate family tree.
  • Keywords
    biology computing; evolution (biological); genetics; information services; GenBank; automated DNA sequencing; family tree; genes piecemeal; genetic sequences; phylogenetics; phylogeny; Animals; Biological information theory; Biology computing; DNA; Databases; Earth; Genetics; Gold; Organisms; Phylogeny; biology; phylogeny; tree of life;
  • fLanguage
    English
  • Journal_Title
    Computing in Science & Engineering
  • Publisher
    ieee
  • ISSN
    1521-9615
  • Type

    jour

  • DOI
    10.1109/MCSE.2005.48
  • Filename
    1425388