تأثير مصرف ويتامين Dطي تمرينات مقاومتي فزاينده بر تغييرات مالون دي‌آلدئيد و آنزيم كراتين‌كيناز در مردان تمرين‌نكرده

The Effect of Vitamin D Consumption during Progressive Resistance Training on Malondialdehyde and Creatine Kinase Changes in Untrained Men

فعاليت‌هاي مقاومتي موجب افزايش فشار اكسيداتيو و آسيب عضلاني مي‌شود. هدف تحقيق حاضر بررسي تأثير ويتامين D طي 8 هفته تمرينات مقاومتي فزاينده بر تغييرات غلظت مالون دي آلدئيد و كراتين كيناز بود. به اين منظور 40 آزمودني مرد 25-20 ساله داوطلبانه در تحقيق حاضر شركت كردند و به‌طور تصادفي در چهار گروه مكمل ويتامينD-تمرين مقاومتي (10=n)، دارونما-تمرين مقاومتي (10=n)، مكمل ويتامينD n=10) و كنترل (10=n) قرار داده شدند. تمرينات مقاومتي فزاينده سه جلسه در هفته و يك روز در ميان به مدت 8 هفته با شدت فزاينده در هشت حركت انجام گرفت. آزمودني‌هاي گروه مكمل ويتامين D-تمرين مقاومتي و همچنين گروه مكمل ويتامين D هر دو هفته يك‌بار يك كپسول 50000 واحدي ويتامين D را تا انتهاي دورۀ تحقيق مصرف كردند. نمونه‌گيري خون پيش و پس از دورۀ تمرينات به‌عمل آمد و از پلاسما براي سنجش فعاليت آنزيم كراتين كيناز و تعيين غلظت مالون دي‌آلدئيد استفاده شد. نتايج نشان داد كه مقادير كراتين كيناز بين هيچ‌كدام از گروه‌ها اختلاف معنا‌داري نداشت (0/05

Resistance exercises increase oxidative stress and muscle damage. The aim of the present study was to investigate the effect of vitamin D on MDA and CK changes during 8 weeks of progressive resistance training. 40 male subjects (age range 20-25 years) participated in the study voluntarily and were randomly assigned to 4 groups: vitamin D-resistance training (RTD; n=10), placebo-resistance training (RTP; n=10), vitamin D (VD; n=10) and control (con; n=10). Progressive resistance training was performed 3 sessions a week, every other day for 8 weeks with eight movements and increased intensity. Subjects in RTD and VD groups consumed a 50000-IU capsule of vitamin D every two weeks. Blood samples were gathered before and after the training period. Plasma was used to assess CK activity and MDA concentration. Results showed no significant difference among the groups in CK (P˃0.05). However, it was observed that MDA changes in group x time interaction was significant (P=0.001), that is to say MDA concentration significantly decreased in RTD group compared with VD (P=0.017) and control (P=0.034) groups. Also, MDA concentration was significantly lower in RTP than VD in the posttest (P=0.045). However, there was no significant difference between RTD and RTP. Finally, it can be said that the combination of resistance training and vitamin D can decrease lipid peroxidation. However, it seems that resistance training role is very important in this regard.