اﺛﺮ ﺗﻤﺮﯾﻦ ﻫﻮازي ﺗﻨﺎوﺑﯽ و ﻣﺼﺮف ﻋﺼﺎره ﮐﺎﺳﻨﯽ ﺑﺮ ﺳﻄﻮح آﻧﺰﯾﻢﻫﺎي ﮐﺒﺪي ﭘﺴﺮان ﭼﺎق ﺑﺎ ﮐﺒﺪ ﭼﺮب ﻏﯿﺮالكلي

Effect of Aerobic Interval Training and Consumption of Chicory Extract on Levels of Liver Enzymes in Obese Boys with Non-Alcoholic Fatty Liver

زﻣﯿﻨﻪ و ﻫﺪف: ﻓﻌﺎﻟﯿﺖ ورزﺷــﯽ و ﺗﻐﺬﯾﻪ ﻗﺎﺑﻠﯿﺖ ﮐﻨﺘﺮل ﺑﯿﻤﺎري ﮐﺒﺪ ﭼﺮب را در ﮐﻮدﮐﺎن و ﻧﻮﺟﻮاﻧﺎن ﭼﺎق دارد. ﻫﺪف ﭘﮋوﻫﺶ ﺣﺎﺿــﺮﺗﺎﺛﯿﺮ ﻫﺸـﺖ ﻫﻔﺘﻪ ﺗﻤﺮﯾﻦ ﻫﻮازي ﺗﻨﺎوﺑﯽ و ﻣﺼـﺮف ﻋﺼـﺎره ﮐﺎﺳـﻨﯽ ﺑﺮ ﺳـﻄﻮح آﻧﺰﯾﻢﻫﺎي آﻻﻧﯿﻦ آﻣﯿﻨﻮ ﺗﺮاﻧﺴـﻔﺮاز و آﺳـﭙﺎرﺗﺎت آﻣﯿﻨﻮ ﺗﺮاﻧﺴـﻔﺮاز ﭘﺴـﺮان ﭼﺎق ﻣﺒﺘﻼ ﺑﻪ ﺑﯿﻤﺎري ﮐﺒﺪ ﭼﺮب ﻏﯿﺮاﻟﮑﻠﯽ ﺑﻮد. ﻣﻮاد و روش ﻫﺎ: 36 ﻧﻔﺮ از داﻧﺶآﻣﻮزان ﭘﺴـﺮ 13 ﺗﺎ 15 ﺳـﺎل ﺑﻪﻃﻮر ﺗﺼـﺎدﻓﯽ ﺑﻪ ﺳـﻪ ﮔﺮوه 12 ﻧﻔﺮه ﺗﻤﺮﯾﻦ + ﻣﮑﻤﻞ، ﺗﻤﺮﯾﻦ + داروﻧﻤﺎ و ﻣﮑﻤﻞ ﺗﻘﺴـﯿﻢ ﺷـﺪﻧﺪ. در ﻫﺮ ﺳـﻪ ﮔﺮوه ﺧﻮن ﮔﯿﺮي ﺑﻪﻋﻨﻮان ﭘﯿﺶآزﻣﻮن و ﭘﺲآزﻣﻮن ﺑﻪ ﻋﻤﻞ آﻣﺪ. ﮔﺮوهﻫﺎي ﺗﻤﺮﯾﻦ ﺑﻪ اﺟﺮاي ﺑﺮﻧﺎﻣﻪ ﺗﻤﺮﯾﻦ ﻫﻮازي از ﻧﻮع ﺗﻨﺎوﺑﯽ ﺗﻮاﺗﺮ 4 ﺟﻠﺴــﻪ در ﻫﻔﺘﻪ و ﺑﻪ ﻣﺪت 8 ﻫﻔﺘﻪ ﭘﺮداﺧﺘﻨﺪ. آزﻣﻮدﻧﯽﻫﺎ در ﻃﯽ اﯾﻦ دوره روزاﻧﻪ 200 ﻣﯿﻠﯽﻟﯿﺘﺮ ﻋﺼــﺎره ﮔﯿﺎه ﮐﺎﺳﻨﯽ ﯾﺎ داروﻧﻤﺎ درﯾﺎﻓﺖ ﮐﺮدﻧﺪ. ﯾﺎﻓﺘﻪ ﻫﺎ: ﻧﺘﺎﯾﺞ آزﻣﻮن آﻧﺎﻟﯿﺰ وارﯾﺎﻧﺲ ﯾﮏ ﻃﺮﻓﻪ ﺗﺤﻘﯿﻖ ﻧﺸـﺎن داد ﺳـﻄﻮح ﺳـﺮﻣﯽ ALT و AST در ﻫﺮ ﺳـﻪ ﮔﺮوه ﮐﺎﻫﺶ ﻣﻌﻨﺎداري ﯾﺎﻓﺖ (0/0001≤ P) و اﯾﻦ ﮐﺎﻫﺶ در ﮔﺮوه ﺗﻤﺮﯾﻦ+ ﻣﮑﻤﻞ در ﻣﻘﺎﯾﺴﻪ ﺑﺎ ﺳﺎﯾﺮ ﮔﺮوهﻫﺎ ﺑﯿﺸﺘﺮ ﺑﻮد (0/05

Background&Purpose: Exercise and Nutrition can control fatty liver disease in obese children and adolescents. The aim of the present study was to investigate the effect of eight-week aerobic interval training and consumption of chicory extract on levels of alanine aminotransferase and aspartate aminotransferase enzymes in obese boys with non-alcoholic fatty liver disease. Methodology: 36 male students aged 13-15 years were randomly divided into three groups of 12 cases: training + supplement, training + placebo, supplement. Blood samples were taken as pretest and post-test in all three groups. Training groups performed aerobics training program comprised of Interval Training, 4 sessions per week for 8 weeks. During the experimental period, participants received either 200 mL daily chicory extractive for 8 weeks or placebo. Results The results of one-way ANOVA showed that serum levels of ALT and AST decreased significantly in all three groups (P<0.0001), and this decrease was higher in training + supplement group than other groups (P<0.05). Conclusion: The results of the research showed that simultaneous consumption of chicory with aerobic interval training can lead to a decrease ALT and AST enzymes,thus aerobic interval training and consumption of chicory extract propose for treatment of patients with nonalcoholic fatty liver