تاثير تمرين شنا همراه با مصرف امگا 3 بر آيريزين و تركيب بدني دختران چاق داراي سندروم داون

Effect of Swimming Training along with Omega-3 Intake on Irisin and Body Composition in Obese Girls with Down Syndrome

ﺧﻼﺻﻪ ﻣﻘﺪﻣﻪ: ﻣﺸﮑﻼت ﻋﺼﺐ ﺷﻨﺎﺧﺘﯽ، ﻣﺘﺎﺑﻮﻟﯿﮑﯽ و ﺟﺴﻤﯽﻫﻤﺎﻧﻨﺪ ﻧﺎرﺳﺎﯾﯽﻫﺎي ﻗﻠﺒﯽ ﻋﺮوﻗﯽ از ﻣﻬﻢﺗﺮﯾﻦ ﻋﻠﻞ ﻣﺮگ و ﻣﯿﺮ ﮐﻮدﮐﺎن ﺳﻨﺪرم داون اﺳﺖ. ﻫﺪف ﭘﮋوﻫﺶ ﺣﺎﺿﺮ ﺑﺮرﺳﯽ ﻣﺼﺮف اﻣﮕﺎ 3 ﺑﻪ ﻫﻤﺮاه 8 ﻫﻔﺘﻪ ﺗﻤﺮﯾﻦ ﺷﻨﺎ ﺑﺮ آﯾﺮﯾﺰﯾﻦ و ﺗﺮﮐﯿﺐ ﺑﺪﻧﯽ دﺧﺘﺮان ﭼﺎق داراي ﺳﻨﺪروم داون ﺑﻮد. روش ﮐﺎر: در اﯾﻦ ﻣﻄﺎﻟﻌﻪ ﻧﯿﻤﻪ ﺗﺠﺮﺑﯽ 18 دﺧﺘﺮ داراي ﺳﻨﺪرم داون )ﺳﺎل12±2وkg/m2 1/3 22± ( ﺑﻪ ﺻﻮرت ﺗﺼﺎدﻓﯽ در دو ﮔﺮوه ﺗﻤﺮﯾﻦ و ﺗﻤﺮﯾﻦ + ﻣﮑﻤﻞ ﺗﻘﺴﯿﻢ ﺷﺪﻧﺪ. آزﻣﻮدﻧﯽﻫﺎ در ﺑﯿﺴﺖ و ﭼﻬﺎر ﺟﻠﺴﻪ ﺗﻤﺮﯾﻦ ﺷﻨﺎ ﺑﺎ ﺷﺪت 45 ﺗﺎ 65% ﺿﺮﺑﺎن ﻗﻠﺐ ﺑﯿﺸﯿﻨﻪ و ﻣﺼﺮف 300 ﻣﯿﻠﯽ ﮔﺮم ﮐﭙﺴﻮل اﻣﮕﺎ 3 )ﮔﺮوه ﺗﻤﺮﯾﻦ + ﻣﮑﻤﻞ( ﺑﻪ ﻣﺪت 8 ﻫﻔﺘﻪ ﺷﺮﮐﺖ ﮐﺮدﻧﺪ، ﻧﻤﻮﻧﻪ ﺧﻮﻧﯽ 24 ﺳﺎﻋﺖ ﻗﺒﻞ از اوﻟﯿﻦ ﺟﻠﺴﻪ ﺗﻤﺮﯾﻨﯽ و 48 ﺳﺎﻋﺖ ﺑﻌﺪ از آﺧﺮﯾﻦ ﺟﻠﺴﻪ ﺗﻤﺮﯾﻦ ﮔﺮﻓﺘﻪ ﺷﺪ. دادهﻫﺎ ﺑﺎ اﺳﺘﻔﺎده از روش آﻣﺎري ﺗﺤﻠﯿﻞ وارﯾﺎﻧﺲ ﺑﺎ اﻧﺪازه ﮔﯿﺮي ﻣﮑﺮر و در ﺳﻄﺢ ﻣﻌﻨﯽداري )0/05≤p( ارزﯾﺎﺑﯽ ﺷﺪ. ﻧﺘﺎﯾﺞ: ﻧﺘﺎﯾﺞ ﭘﮋوﻫﺶ ﻧﺸﺎن داد ﮐﻪ ﭘﺲ از 8 ﻫﻔﺘﻪ در ﮔﺮوه ﺗﻤﺮﯾﻦ + ﻣﮑﻤﻞ ﺳﻄﻮح آﯾﺮﯾﺰﯾﻦ ﺳﺮﻣﯽو ﺗﻮده ﻋﻀﻼﻧﯽ ﺑﻪ ﻃﻮر ﻣﻌﻨﺎداري )0/05< P( اﻓﺰاﯾﺶ ﯾﺎﻓﺘﻪ و ﻣﯿﺰان ﭼﺮﺑﯽ ﮐﺎﻫﺶ ﻣﻌﻨﺎدار ﯾﺎﻓﺖ)0/05

Introduction: Neurological, metabolic and physical problems such as cardiovascular insufficiency are of the most important causes of deaths in children with Down syndrome. The aim of this study was to evaluate omega-3 intake along with eight weeks of swimming training on irisin and body composition in obese girls with Down syndrome. Materials and Methods: In this semi-experimental study, 18 girls with Down syndrome (12 ±2 years and 22± 1.3 kg / m2) were randomly divided into two groups of exercise training and exercise training + supplements. The subjects participated in twenty-four sessions of swimming training with an intensity of 45-65 percent maximal heart rate and consumption of 300 mg omega-3 capsule (exercise group + supplement) for 8 weeks. Blood samples were taken 24 hours before the first training session and 48 hours after the last training session. Data were analyzed using repeated measures ANOVA. P≤ 0.05 was considered statistically significant. Results: The results showed that in the supplementation group, the levels of serum irisin and muscle mass significantly increased after 8 weeks (P <0.05) and the amount of fat significantly decreased (P <0.05). Conclusion: It seems that swimming training and omega-3 supplement in children with Down syndrome can reduce the risk of cardiovascular diseases and improve many of their motor limitations by affecting body composition. Funding: This research was funded by East Tehran Branch, Islamic Azad University, Tehran, Iran.