بررسي اپيدميولوژيك سرمي سرخجه و تعيين شاخص هاي اپيدميولوژيك از طريق بررسي مبتني بر جامعه در جمعيت غيرواكسينه صفر تا 45 ساله شهرستان اروميه 1380

A COMMUNITY BASED RUBELLA SEROEPI- DEMIOLOGIC SURREY AND EPIDEMIOLOGI- CAL INDICATORS DETERMINATION IN THE 0-14 YEARS OLD NON-VACCINATED POPULATION-URMIA 1380

Introduction : To determine age-specific. rubella seroprevalcncc in the 0 to 45 years-old unvaccinated population in Urmia, Iran and also to papose a vaccination strategy against rubella. Materials & Metheds : A total of 1600 unvaccinated propos 0 to 45 years old were selected for the study with cluster sampling. Sera from 751 females and 781 males were tested for rt..thella IgG antibody using enzyme linked imnuaiosorbenl assay (ELIZA) technique. "Rubella scroposllit ils" was defined as serum rubella IgG antibody level> or = 13 IL/ml. Results : Of the 1539 cases, 61.5% were seroposhi-ve. Due to mathernal derived antibodies, 93.3% of the newborns was seropositive. This figure decreased with time until it became zero in childreen aged 10 months, then from years 4, increased with age gradually until it peaked at 92.8% in the age group of 30-34 years. Then the seropositivity decreased 88.9% in the age group of >35 years. Of women in the reproductive age groups (15-45 years old), 89.2% were seropositive. Discussion : Because a substantial proportion of women in their childbearing years are susceptible to rubella, immunization efforts should be directed at infants and / or prepubertal children.