گزارش يك مورد اوتيسم با هترومورفيسم كروموزوم 15 مادري

A CASE OF AUTISTIC BOY WITH HETEROMORPHISM OF MATERNAL NUMBER 15 CHROMOSOME

Introduction : Infantile autism is a clinical heterogenous disorder with unknown etiology. Evidences from the relatively few family and twin studies suggest a genetic component. It is concluded that in some cases chromosomal rearrangements are the basic causes. The aim of the present work is to report a 4-year-old autistic boy with a genetic approch. Materials & Methods: Family history, pedigree pattern and chromosomes of the proband and his parents were studied (G-banding). Results: There was no any other case in his family history. Chromosomal study has revealed a maternal origin rearranged chromosome number 15. Conclusion: The results of present study confirmed that chromosomal study is one of the first necessities in the study of autism, and it will help us for a better genetic counseling with families with an autisic child.