تعيين مقدار سرب در ترياك به روش طيف سنجي جذب اتمي شعله اي

Determination of Lead in Opium by Flame Atomic Absorption Spectrophotometery

Background: Adulterants can reinforce toxic effects of opioids. Lead is an important impurity of opium which induces adverse effects in opium abusers. The purpose of present study was determination of lead impurity in opium by flame atomic absorption spectrophotometry. Methods: After wet digestion of opium samples by nitric acid, standard solutions of lead were prepared and calibration curve was plotted. Then concentration of lead content in opium samples was measured. Finally interday and intraday precision, limit of detection and limit of quantitation were evaluated. Results: This method is suitable for analysis of lead impurity of opium in 5-40 ppm concentration range. The interday and intraday precision in this method was 0.8 and 1.2%, respectively. Limit of detection and limit of quantitation in this method was 2 ppm and 5 ppm, respectively. Conclusion: Flame atomic absorption spectrophotometery is a suitable method for determination of lead impurity in opium.