41 C - سنتز سم علفكش 2و4 دي كلروفنوكسي استيك اسيد كربوكسي

Synthesis of 2, 4- Dichloro Phenoxy Acetic Acid [Carboxy-14C] as Herbicide

One of the important herbicide, that can be used for the practical mechanism investigations and studies of metabolism functions of different plants is 2,4 dichlorophenoxy acetic acid compound .In this article, the production method for labeling the titled compound is explained. At the first stage of this research work, barium [14C] carbonate is converted into potassium [14C] cyanide by using potassium azid at a reasonable temperature. Then, after a few synthesis reaction, the compound 2,4 dichlorophenoxy methyl iodide is produced via 2,4 dichlorophenoxy as a starting material. At the next stage, the real material as a herbicide: 2,4 dichlorophenoxy acetic acid [carboxy- ^C] is prepared and produced, by the coupling reaction between 2,4 dichlorophenoxy methyl iodide and potassium [^C] cyanide, and then the resulting nitrile has been hydrolyzed.