بررسي تاثير كورتيكو استروييد درماني بر ضايعات ته چشمي بيماران مبتلا به كوليت اولسروز در بيمارستان فارابي

EFFECTS OF STEROID THERAPY ON FUNDUS LESION IN PATIENTS WITH ULCERATIVE COLITIS IN FARM EYE HOSPITAL

Owing to the relatively non understanding of eye symptoms such as funduscopic appearances in patients with ulcerative colitis, this study was conducted to describe the clinical course and Lesions in the posterior segment in patients treated with oral steroids. This research was conducted on patients referred to Farabi hospital during the years 1991-1998 . Patients were evaluated regarding demographic variables, posterior segment presentations, prior treatments and clinical outcome. In all patients, oral steroids were advised. The effect of treatment following 6 month was assessed by funduscopic examination and visual acquity testing and analyzed by Mac- nemar. 15 patients(7 Male and 8 female) with age ranging between 19.5-26.5 were assessed during ai 7 year period . In 46.7!x, of patients eye presentations included retinal detachment with choroidal infiltration. Visual acquity equal to more than 3.10 improved from 23% to 50% following oral steroid medication (p<0.001). Since oral steroids result in improvement and a reduction in posterior segment manifestations in patients with ulcerative colitis, the gastroenterologists are requested to refer the patients to ophthalmologists if eye manifestations of ulcerative cofitis or other diseases of IBD group are observed.