بررسي تاثير كرايوتراپي در درمان ويتليگوي لوكاليزه

Treatment of Localized Vitiligo with Cryotherapy

Background and Objectives: Vitiligo is a common idiopathic disease, associated with loss of normal melanin pigment and functioning melancoytes. We conduct this survey to reach an easy and effective treatment for vitiligo. Materials and Methods: In this study, liquid nitrogen used for 5 seconds in 6 times with 2 weeks intervals, for treatment of localized vitiligo at Sina Hospital in Tabriz. Results: 24 cases with 50 depigmented patches smaller than 6 cm, treated and followed up. Two weeks after therapy, the lesions assessed and analyzed. Complete repigmentation was occured in 22 patches (44%); pigmentation > 50% was observed in 15 patches (30%) and pigmentation <50% was noticed in 10 patches (20%). Only in 3 lesions (6%) pigmentation was not occurred. Efficacy of this approach in study groups, was statistically significant (p< 0.05). Conclusion: Efficacy of cryotherapy in localized vitiligo was significant, and this method could be used as an alternative or complementary therapy in localized vitiligo.