بررسي وجود آنتي بادي كارديوليپين در بيماران دچار حوادث حاد ايسكمي قلبي

Anticardiolipin antibody in patients with ischemic events

Background and purpose: In order to determine the presence of anticardiolipin (acl) antibodies in patients with ischemic events, a case control study was designed and performed. Materials and methods: 33 patients with unstable angina, 33 male patients with myocardial infarction and 34 persons with no evidence of ischemic heart disease were selected for this study. Plasma samples were assessed for detection of the level of IgG acl antibody by ELISA method. Results : The level of cardiolipin (mean ± SD of optical density multiplied by 1000) for unstable angina, myocardial infarction patients and control subjects were 624 ± 3.19, 486 ± 318, and 239 ± 2.2 respectively. P=0.0001 and F=15.74. Conclusion: The results of this study indicate that the level of ad antibody in the patients with ischemic event is higher than the other groups.