تاثير روزه ماه مبارك رمضان بر پاسخ ازدياد حساسيت تاخيري نسبت به PPD

The Effect of Holly Fasting Month of Ramadan on the Delayed Type Hypersensitivity Response to Purified Protein Derivative

Studies during recent decade indicate that low calorie intake has potentiating effect on immune response . So the effect of fasting in holly month of Ramadan on cellular immune was studied. In this study , delayed type hypersensitivity (DTH) to purified protein derivative (PPD) test was selected to evaluate cellular immune response , because this test is not only very simple but also is valuable and reliable. This research studied DTH to PPD in two groups of students before and after ^he holly fasting month of Ramadan. The range of age in the both groups was 20-30 year. Mantoux method was the selected method to evaluate DTH response to PPD. DTH response to PPD in fasting group increased from 8.8 to 13 mm , which is statistically significant (P<0.05). It is noticeable that the differences between the rates of increasing DTH response to PPD in control group and fasting group was statistically significant (P<0.05). Based on the above finding it can be concluded that fasting has potentiating effect on cellular immune response.