بررسي 5ساله اپيديديموار كيت بروسلايي در بيماران بستري در

Background and purpose: Epididymoorchitis is a focal form of human Brucellosis , described in %2 - 20% of patients with Brucellosis . Materials and methods : In this retrospective study, we report 18 cases of Brucella epididymoorchitis in Qaem shahr Razi hospital and Sari Imam komeini hospital . between 1376 -- 1380. Agglutination titres > 1/160 and positive clinical manifestation, of Brucella epididymoorchitis were the main criteria of diagnosis. Results: Epididymoorchitis has occurred in 13.04% of the male patients with Brucellosis. mean mediam age of the patients was 27 years. (rangings from 14 to60). Pain and scrotal swelling (100%), fever (100%) and sweating (73%) were the most common symptoms. All patients had agglutination titers of > 1:160 (range, 1:160 - 1:2560) and 2ME (range, 1:80 - 1:640) . Combined therapy was as follow: doxcyclin with rifampin (61.1) or doxycyclin plus rifampin along with aminoglycoside for the first two week, (27.7%) and doxyycyclin plus cotrimixazole (5.5%) and doxycyclin aline( in 5.05%).Treatment consisted of a combination of doxycyclin and Rifampin with aminoglycoside (for the first 2 weeks of therapy). (27.77), trimethoprime-sulfamethoxazole with doxycycline (5.05%) or doxycyclin as monotherapy (5.05%). The minimal duration of therapy was 45 days. 88.8% of patients showed no improvement to antibiotics and required surgical drainage and orchiectomy. Conclusion: In Brucellosis endemic areas, clinicians encountering epidiymoorehitis should consider the likelihood of Brucellosis. A careful history of patients, a proper physical exame and a immediate laboratory evaluation help in diagnosis. Clinical and serological data are sufficient for diognosis. Generally, classical therapy of Brucellosis is adequate for the treatment of epididymoorchiti.