تهيه و تعيين اعتبار نسخه فارسي آزمون كوتاه وضعيت ذهني

Validity of the Farsi Version of Mini-Mental State Examination

Diagnosis of dementia in early stages improves treatment outcomes and reduces disease burden. Mini-mental state examination (MMSE) is a widely used instrument for diagnosis and screening of dementia in western countries and many other countries. Aim of this study was to prepare and validate the Farsi version of MMSE (F-MMSE). First, MMSE was translated to Farsi. We made some changes in language-related items to improve face validity of test. F-MMSE was applied to 30 patients with dementia and 200 healthy individuals. F-MMSE score in patients with dementia ranged from 1 to 26 with a mean of 13.6 and standard deviation of 6.17. Range of score in healthy subjects was from 18 to 30 with a mean of 26.3 and standard deviation of 2.79. Based on t-test, there was a significant difference between two groups. Using ROC curve, a cut-off point of 22 showed a sensitivity of 90 and specificity of 93.5 percent. It seems that F-MMSE has acceptable validity and a cut-off point of 22 can reliably differentiate patients with dementia from healthy subjects