بررسي پنج ساله بيماران با ديابت نوع 1 بستري شده به دليل كتواسيدوز ديابتي در مركز آموزشي، درماني بوعلي سيناي قزوين (1378-1383

Evaluation of clinical manifestation, laboratory data and precipitating factors in patients with Diabetic ketoacidosis in educational and medical care center of Booali Sina in Ghazvin (1999-2004)

Background and aim: Diabetic ketoacidosis is one of the major complications of diabetes whose due treatment can reduce its mortality. The aim of this study was to evaluate the clinical manifestation, laboratory data and precipitating factors in admitted patients to Booali hospital in Ghazvin. Materials and Methods: In this descriptive retrospective study, all medical files of DKA patients between 1999 and 2004 in Ghazvin Booali hospital were surveyed. Totally, 60 episodes were evaluated with respect to clinical features, lab. findings and hospital mortality. Finally, the obtained data was statistically analyzed by means of SPSS software. Results: Mean±SD age of patients was 26.63± 11.74. Females and males were 60% and 40%, respectively. Mean±SD hospitalization time was 7.2±3.9 days. DKA as the first symptom of diabetes occurred in 18.3% of clients. Feebleness and weakness were the most common complaint in 50% of patients, 75% were alert to their problem when hospitalized. Fever was detected in 50 %.The mean PH was 7.1±0.1. Hyponatremia occurred in 25%, urinary tract infection (UTI) in 54%, and hypoglycemia in 23% of the patients. During management, recurrent DKA was found in 3.3% and mortality rate was 5%. Conclusion: Regarding the results of the study, which confirms lack of knowledge of the clinical staff as to how to confront and manage DKA-as a medical emergency due education in this field can reduce prevalence and mortality of DKA.