جداسازي و تعيين الگوي مقاومت آنتي بيوتيكي سالمونلا تيفي موريوم

Isolation and antibiotics resistance pattern determination of Salmonella typhimurium

Aims. Salmonellae infection is one of the most important food-borne diseases. Antimicrobial resistance is increasing among Salmonella spp. and causes significant therapeutic problems in the treatment of diseases caused by this organisms. The aim of current study was to determine the isolation rate and antimicrobial susceptibility of Salmonella enterica subsp. enterica serovar typhimurium strains. Methods. Salmonella spp. strains were isolated from clinical cases from May 2007 to June 2008. The susceptibility of the isolates to eight antibiotics was determined according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Results. Among all Salmonella isolates, 21 (15.2%) strains were identified as Salmonella enterica subsp. enterica serovar typhimurium. More than 66% of the strains were resistant to Chloramphenicol, 57.1% to Ampicillin, 23.8% to Co-trimoxazole, 14.3% to Neomycin, 9.5% to Nalidixic acid and no resistance reported to Ceftriaxone, Ciprofloxacin and Gentamicin. Conclusion. S. typhimurium is one of the most prevalent non-typhoidal Salmonella serovars circulating in Tehran. Ceftriaxone, Ciprofloxacin and Gentamicin were effective against Salmonella and can be considered for treatment of infections caused by this organism.