بررسي اثر درماني ويتامينB6در درمان علائم گوارشي ديسمنوره اوليه دختران جوان در شهرستان يزد در سال 1384-1387

Therapeutic Effect of Vitamin B6 on Gastro-Intestinal Symptoms of Primary Dysmenorrhea in Young Women in Yazd City (2006-2009)

Introduction: Dysmenorrhea is painful cramps which happen just before or at [Iter start point of menstruation wilhuut organic reason, which is occasionally accompanied in ga si rainiest iua I problems. This study was performed in order to examine tht > peulie e"ii:cʹ nf vit unin B6 on gastro-inteslinal symptoms such as nausea and vomiting di c to primary dysmenorrhea. Methods: Present study is a double blind case-conln 1 ...: :• d/.ed study mi gʹ.i . aged between 1 S-17 years with primary dysmenorrhea who rclʹt ■ d lo nccnln ʹic clini. ■ of Shahid S idoughi Yazd in years 2006-2008. 180 girls who had pusl i tesiinnl symptoms tccompanying dysmenorrhea selected and were divi-i.-d into 2 groi ps: Viiiim i B6 tjroup (Iv 9U) who received , lOOmg vitamin Li 6 (two 50 mg cap ile ) daily u lltfe it pit ise lor 3 months mi pi ?.. ■ > grui p ; (N: 90) who received two placebo capsules similar so vitamin 1V> for 3 months. Data \va; analyzed by SPSS 11 using I t si and Chi sqinie test Results: Vitamin B6 reduced nausea of dysmenorrh. :ʹ-: J.2% and placebo effect was 10% (P 0.001). Vomiti i was reduced 64.4% in ■■ ■ imin Ufi up ti 26.6% in placebo respective!} (P=0.001). No clrvii. - idc effect was seen in any of gnnips Conclusion: Vitamin B6 can be use as an effective drug on gastro-intest naJ symptoms ol : prim;-.1; I dysmenorrhea.