Author/Authors :
Jun Liu، نويسنده , , Jian Shi، نويسنده , , Lianmei Jiang، نويسنده , , Fan Zhang، نويسنده , , Li Wang، نويسنده , , Shinpei Yamamoto، نويسنده , , Mikio Takano، نويسنده , , Mengjie Chang، نويسنده , , Haoli Zhang، نويسنده , , Yong Chen، نويسنده ,
Abstract :
We report a simple but straightforward approach to fabricate magnetic nanofiber segments for cell manipulation. Electrospinning was used to produce nanofibers from a magnetic nanoparticles containing polymethylglutarimide (PMGI) precursor solution. After sonication, the fabricated nanofibers were uniformly segmented. When dispersed in an aqueous solution, the orientation of the fiber segments could easily be controlled by an external magnetic field. NIH 3T3 cells were then cultured in a medium containing magnetic fibers, resulting in stable cell-nanofiber hybrids which can be conveniently manipulated with a magnet.
